Connectivity Course: Structural and Functional Brain Connectivity via MRI and fMRI

October 2022 course has been postponed until October 2023


Issues associated with “connectivity” within the human brain are growing in importance. This can be seen in the significant number of abstracts, research articles and even entire journals devoted to this area, as well as in the increased emphasis on lesions in connections as a source of many neuro-psychiatric disorders. MRI has proven to be a valuable tool for examining connectivity both in terms of the coordinated activities of neural networks (using BOLD-based fMRI data collected during rest and during tasks) and in terms of the structural anatomy of white matter pathways of the brain (using Diffusion Tensor Imaging (DTI), Diffusion Spectrum Imaging (DSI) and Tractography to analyze and visualize the resulting data).

In this program, participants will learn about the technical challenges in acquisition, data processing and visualization of brain networks via functional MRI data. They will also receive a firm grounding in the power and limitations of using diffusion-sensitive MRI to detect and organize the anatomical structure of white matter tracts in the living human brain.  There will be at least three lectures on state-of-the-art clinical/research applications.

The primary goal of the program is to give researchers and clinicians a good “running start” for their investigations using these tools. In that sense, it serves a purpose analogous to that of the long-running Martinos Center’s Functional MRI Visiting Fellowship Program (fMRIVFP), with the exception that the domain will be structural and functional connectivity of myelinated fiber tracts within the living human brain.

While various data analysis and software-related issues will be discussed, this is not a software training program.  The Martinos Center offers two programs to give thorough software training in each of the two main areas: functional analysis (via the “Learning the Conn Toolbox”, a 5-day course), and structural analysis (via the “Hands-On Diffusion MRI” course, a 4 or 5 day course (still being developed).

The core faculty for the program is drawn from the staff of the Athinoula A. Martinos Center (of the Massachusetts General Hospital and Massachusetts Institute of Technology) and affiliated faculty from Harvard University, McLean Hospital, The Brigham and Womens Hospital, and other institutions. Guest lecturers in the past have included representatives of the NIH, the Child Mind Institute of New York and others.



Registration is not open at this time for the 2023 course.


Connectivity Fall 2022