October 19-23, 2026
In person workshop, Martinos Center, 149 13th St Charlestown MA
The pioneering work of the Martinos Center spurred an explosion of research in functional brain imaging. While we have known for almost 100 years that neural activity causes localized changes in blood flow, and researchers have more recently demonstrated that neural activity causes localized changes in blood oxygenation, the tools for measuring these signals have historically been highly invasive in animals and moderately invasive in humans. The seminal work of an extraordinary team of physicists, radiologists and neuroscientists at the Martinos Center, demonstrating that these changes and blood flow and blood oxygenation can be detected by the noninvasive technology of MRI, has led to a dramatic increase in functional brain imaging work with humans. Because this noninvasive technique permits many repetitions of experimental procedures on a single subject, it is rapidly becoming the method of choice for neuroscience research in functional brain mapping. The purpose of the present course is to provide an in-depth introduction to this field. It is primarily intended for people new to functional MRI, though experienced scientists have also found the program useful.
Curriculum
Students will receive a firm grounding in the fundamentals of fMRI. This will include the basic physics of MR imaging, the biology and biophysics of the hemodynamic responses to neural activity, data analysis (including both exploratory and statistical analyses), stimulus presentation and response recording in the context of high magnetic fields and electromagnetic pulses, and the design of perceptual and cognitive experiments. Other topics include issues of structural and functional connectivity and the importance of large scale databases containing high-quality functional and structural MRI-based and behavioral data for hundreds and even thousands of subjects. The core faculty is drawn from the staff of the Athinoula A. Martinos Center (of the Massachusetts General Hospital and Massachusetts Institute of Technology) and affiliated faculty from Harvard University, Boston University, McLean Hospital and other institutions.
This workshop discusses data analysis for fMRI-based experiments in great detail. However, it is NOT a training workshop for any specific software package. Rather, it examines the topics that are critical for ANY software package that analyses task-based fMRI experiments. Packages such as AFNI, BrainVoyager, Freesurfer, FSL, and SPM are all mentioned, but the emphasis is on the topics that they (and others) share, with regard to the concepts that are important in analyzing experiments. Each of those software packages offer their own intensive, software-specific workshops to address the details of using them, but they all basically use the same kinds of tools and those tools are discussed at length in the Martinos workshop.
Registration
Schedule from 2024
Schedule_20241021 fMRI Course PreCourseDraft.pages
contact fmrivfp@mgh.harvard.edu with any questions